On the 20th floor of the Tower, the "Regulars" who have been permitted to enter have to undertake arduous and extremely expensive tests to rank up. Most abandon hope and choose to stay where they are—but not Ja Wangnan. Wangnan is determined to reach the top and become the king of the Tower. However, he is weak and has repeatedly failed the exam, with debt collectors tailing him. In desperation, he attempts the exam one more time, only to encounter a mysterious and powerful individual: Jyu Viole Grace, a member of the crime syndicate FUG. Cursing his rotten luck, Wangnan has no choice but to form alliances with strong people, including Viole—who still refuses to be part of any team. Amid a dire situation, Wangnan must find a way to change Viole's mind to finally advance past the 20th floor, or he will never get a chance to build his legacy.

After an awe-inspiring battle with Ichibei Hyousube—leader of the Soul Society's Royal Guard—the powerful Yhwach moves into the final stage of his master plan. He aims to slay the Soul King, the being whose very existence maintains the status quo of three worlds: Hueco Mundo, the Soul Society, and the realm of humans that Ichigo Kurosaki and his closest friends hail from. Conquering his own bout with the remainder of the Royal Guard, Uryuu Ishida joins Yhwach in his efforts to create a new world in his image. With a flood of resolution and newfound power, Ichigo rushes to stop Yhwach from accomplishing his ultimate goal and save the countless lives within the three existing realms. But Ichigo has a complicated lineage, one that leaves him susceptible to Yhwach's sinister influence. Meanwhile, in a final desperate gambit, Jirou Sakuranosuke Shunsui Kyouraku, the newly promoted head captain of the Soul Society's combat corps, enlists the help of an old enemy whose immense power may turn the tide of battle.

With Rabbi Village greatly expanding under the management of his subordinates Isami Tahara and Yuu Kirino, Hakuto Kunai can now resume his adventures while looking for items to counteract magic. He begins his search at the Prison Labyrinth in Rookie Town, where a secret laboratory deep within the dungeon gives him insight into technology that is far more advanced and dangerous than anything in the rest of the world. Meanwhile, Rabbi Village has gained unwanted international attention from the newly formed Queendom of Xenobia, which wishes to drive a wedge between the Holy Kingdom of Light and the State of Right. But with Kunai's newly summoned aide, Akane Fujisaki, at his disposal, things may not go as the Queendom plans.

Demonic activity worldwide has significantly increased due to the involvement and corrupt practices of the Illuminati. To combat the unnatural influx of demons, the Vatican Headquarters decides to hold the annual Exorcist Certification Exam early and allow for as many exorcists as possible to take up the mantle. Straight from the Vatican, one of the most powerful exorcists, Lewin "Lightning" Light, arrives at True Cross Academy to help prepare the students for the exam. The ease and mastery with which Lewin performs exorcisms quickly impresses Ryuuji "Bon" Suguro, who has lost his ambition to continue his studies, and Lewin surprisingly accepts him as his apprentice. Amid the worsening situation, twin brothers Rin and Yukio Okumura are sent to locate the recently missing exorcist Shura Kirigakure, who seems to be chained to a decades-long contract with a powerful, immortal demon hiding in Aomori Prefecture's dangerous, snowy mountains.