Infected Digimon—digital monsters who have begun acting in a berserk manner and experiencing a bizarre increase in power—are invading the real world. While Maki Himekawa and Daigo Nishijima, agents of the mysterious Incorporated Administrative Agency, attempt to learn more about these disruptive appearances, most of the Chosen Children are busy preparing for Tsukishima General High School's summer festival.

Mimi Tachikawa, having recently returned to Japan after living in the United States for years, struggles to find her footing among her classmates and fellow Chosen Children. Meanwhile, by throwing himself into his studies, Jou Kido has been deliberately avoiding all issues related to Digimon, causing his partner Gomamon to run away. Mimi and Jou's individual actions cause friction within the group even as the threat of infected Digimon still looms over them. Will the two resolve their personal conflicts in time to help their friends fight off the latest threat?

[Written by MAL Rewrite]

Tucked away in the darkest depths of this world, tales of the bizarre and the supernatural quietly unfold. These inexplicable stories are chronicled throughout the pages of a certain strange encyclopedia, sheltered within a crumbling, decrepit building. Do you dare to open its cover and experience the horrors firsthand? Each of the macabre tales held within the book's pages details some unusual, surreal experiences that often come to a gruesome end. A man searches for his adulterous wife, only to find himself at the mercy of otherworldly visitors; a boy befriends a snowman who harbors a sinister secret; crop circles suddenly form on a family farm, created by some unexpected visitors; hidden in plain sight, menacing mechanical beings continue on undetected. In all of these horrifying stories, nothing is as simple as it seems, revealing a terrifying darkness that perhaps might have been best left alone. [Written by MAL Rewrite]

Following the first season, Tomoharu is now faced with a dilemma: if he doesn't form a contract with an "akuma," he risks losing his dear friend Takatsuki. However, doing so would compromise his own existence as it would result in him and his ghost friend Misao becoming an Asura Cryin'—mankind's biggest threat, according to their school's presidents. To make the decision even harder, Tomoharu and Misao have recovered some of their past memories—memories of a world that they didn't even know existed.

The world of psychology is far from strange to the unusual Dr. Ichirou Irabu, a resident psychiatrist of Irabu General Hospital. He and his charming nurse Mayumi run through several patients, each suffering from a mental illness that harms their everyday life. Patients should be wary of the seductive Mayumi, with her spellbinding looks and devilishly short pink nurse uniform. On the other hand, the doctor seems to have three separate personalities: a child with an oversized lab coat; an intelligent, youthful man with feminine traits; and a selfish, outgoing green bear. While curing his patients in questionable ways, Dr. Irabu often tries to gain something from them outside of his profession—and in doing so, occasionally forgets his role as a doctor. As each patient struggles to face the nature of their distress, an obvious yet invisible thread ties their paths together.